Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center.

ABSTRACT:

Importance

Spitzoid lesions are a group of melanocytic tumors characterized by spindle-like or epithelioid cells with variable malignant potential. While some spitzoid lesions are classified as evidently benign or malignant by clinic and histology, others present with unclear clinical and histological characteristics and are categorized as lesions of intermediate biologic potential. These lesions represent a challenge for pathologists and clinicians alike. No consensus on ancillary diagnostics and clinical management exists. Prediction of their clinical course is difficult. The implementation of ancillary diagnostics is currently subject of extensive discussions.

Observations

We report three cases of spitzoid lesions in three young female patients (3-, 15- and 17 years old)

SUBMITTER: Hilbers ML 

PROVIDER: S-EPMC7825637 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature