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The role of asymptomatic and pre-symptomatic infection in SARS-CoV-2 transmission-a living systematic review.


ABSTRACT:

Background

Reports suggest that asymptomatic individuals (those with no symptoms at all throughout infection) with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are infectious, but the extent of transmission based on symptom status requires further study.

Purpose

This living review aims to critically appraise available data about secondary attack rates from people with asymptomatic, pre-symptomatic and symptomatic SARS-CoV-2 infection.

Data sources

Medline, EMBASE, China Academic Journals full-text database (CNKI), and pre-print servers were searched from 30 December 2019 to 3 July 2020 using relevant MESH terms.

Study selection

Studies that report on contact tracing of index cases with SARS-CoV-2 infection in either English or Chinese were inclu

SUBMITTER: Qiu X 

PROVIDER: S-EPMC7825872 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature