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Heat inactivation of the severe acute respiratory syndrome coronavirus 2.

ABSTRACT: Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2 could be inactivated in less than 30 min, 15 min, and 3 min at 56 °C, 65 °C, and 95 °C, respectively. These data could help laboratory workers to improve their protocols by handling the virus in biosafety conditions.

SUBMITTER: Batejat C 

PROVIDER: S-EPMC7825878 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Heat inactivation of the severe acute respiratory syndrome coronavirus 2.

Batéjat Christophe C   Grassin Quentin Q   Manuguerra Jean-Claude JC   Leclercq India I  

Journal of biosafety and biosecurity 20210123 1

Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2 could be inactivated in less than 30 min, 15 min, and 3 min at 56 °C, 65 °C, and 95 °C, respectively. These data could help laboratory workers to improve their protocols by handling the virus in biosafety conditions. ...[more]

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