In-silico network-based analysis of drugs used against COVID-19: Human well-being study.

ABSTRACT:

Introduction

Researchers worldwide with great endeavor searching and repurpose drugs might be potentially useful in fighting newly emerged coronavirus. These drugs show inhibition but also show side effects and complications too. On December 27, 2020, 80,926,235 cases have been reported worldwide. Specifically, in Pakistan, 471,335 has been reported with inconsiderable deaths.

Problem statement

Identification of COVID-19 drugs pathway through drug-gene and gene-gene interaction to find out the most important genes involved in the pathway to deal with the actual cause of side effects beyond the beneficent effects of the drugs.

Methodology

The medicines used to treat COVID-19 are retrieved from the Drug Bank. The drug-gene interaction was performed using the Drug Gene I

SUBMITTER: Attique Z 

PROVIDER: S-EPMC7825994 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature