Prebiotic Colloidal Oat Supports the Growth of Cutaneous Commensal Bacteria Including S. epidermidis and Enhances the Production of Lactic Acid.

ABSTRACT:

Background

Multiple skin conditions have been associated with alterations in the diversity and composition of the skin microbiome, including dry skin and atopic dermatitis. In these conditions, a number of commensal skin bacteria have been implicated in supporting a healthy skin barrier, including Staphylococcus epidermidis. Recent clinical studies in patients with mild-to-moderate atopic dermatitis and dry/itchy skin have shown significantly improved skin barrier function and microbial diversity upon treatment with moisturizers containing 1% colloidal oat. We hypothesized that direct use of colloidal oat by skin microbes contributes to these therapeutic benefits.

Methods

Skin bacterial growth was assessed using the BacT/ALERT system. Staphylococcus aureus and

SUBMITTER: Liu-Walsh F 

PROVIDER: S-EPMC7826061 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature