Predictive Ki-67 Proliferation Index of Cervical Squamous Cell Carcinoma Based on IVIM-DWI Combined with Texture Features.

ABSTRACT:

Purpose

This study aims to determine whether IVIM-DWI combined with texture features based on preoperative IVIM-DWI could be used to predict the Ki-67 PI, which is a widely used cell proliferation biomarker in CSCC.

Methods

A total of 70 patients were included. Among these patients, 16 patients were divided into the Ki-67 PI <50% group and 54 patients were divided into the Ki-67 PI ≥50% group based on the retrospective surgical evaluation. All patients were examined using a 3.0T MRI unit with one standard protocol, including an IVIM-DWI sequence with 10 b values (0-1,500 sec/mm²). The maximum level of CSCC with a b value of 800 sec/mm² was selected. The parameters (diffusion coefficient (D), microvascular volume fraction (f),

SUBMITTER: Li C 

PROVIDER: S-EPMC7826202 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature