Skeletal muscle and adipose tissue changes in the first phase of treatment of pediatric solid tumors.

ABSTRACT: Body composition is increasingly recognized as an important factor in cancer outcomes. Use of computed tomography (CT) in cancer care provides the opportunity to accurately quantify whole-body lean and adipose tissues from images at the third lumbar spine. We sought to substantiate the use of routinely captured, single-slice chest CT images at the thoracic level for evaluation of skeletal muscle, residual lean tissue, and adiposity among pediatric solid tumor patients. We performed a retrospective analysis among children who underwent treatment for a solid tumor at Columbia University Irving Medical Center. Skeletal muscle (SM), residual lean tissue (RLT), and adipose tissue cross-sectional areas (cm² ) were analyzed at diagnosis and at first follow-up for disease evaluation (6-

SUBMITTER: Joffe L 

PROVIDER: S-EPMC7826460 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature