Altered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food Components.

ABSTRACT: The interplay between diet and gut microbiota has gained interest as a potential contributor in pathophysiology of irritable bowel syndrome (IBS). The purpose of this study was to compare food components and gut microbiota patterns between IBS patients and healthy controls (HC) as well as to explore the associations of food components and microbiota profiles. A cross-sectional study was conducted with 80 young adults with IBS and 21 HC recruited. The food frequency questionnaire was used to measure food components. Fecal samples were collected and profiled by 16S rRNA Illumina sequencing. Food components were similar in both IBS and HC groups, except in caffeine consumption. Higher alpha diversity indices and altered gut microbiota were observed in IBS compared to the HC. A negative correl

SUBMITTER: Barandouzi ZA 

PROVIDER: S-EPMC7827153 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature