Inflammatory Cytokines in Cancer: Comprehensive Understanding and Clinical Progress in Gene Therapy.

ABSTRACT: The relationship between chronic inflammation and neoplastic diseases is not fully understood. The inflammatory microenvironment of a tumor is an intricate network that consists of numerous types of cells, cytokines, enzymes and signaling pathways. Recent evidence shows that the crucial components of cancer-related inflammation are involved in a coordinated system to influence the development of cancer, which may shed light on the development of potential anticancer therapies. Since the last century, considerable effort has been devoted to developing gene therapies for life-threatening diseases. When it comes to modulating the inflammatory microenvironment for cancer therapy, inflammatory cytokines are the most efficient targets. In this manuscript, we provide a comprehensive review of the

SUBMITTER: Lan T 

PROVIDER: S-EPMC7827947 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature