Unravelling Genetic Factors Underlying Corticobasal Syndrome: A Systematic Review.

ABSTRACT: Corticobasal syndrome (CBS) is an atypical parkinsonian presentation characterized by heterogeneous clinical features and different underlying neuropathology. Most CBS cases are sporadic; nevertheless, reports of families and isolated individuals with genetically determined CBS have been reported. In this systematic review, we analyze the demographical, clinical, radiological, and anatomopathological features of genetically confirmed cases of CBS. A systematic search was performed using the PubMed, EMBASE, and Cochrane Library databases, included all publications in English from 1 January 1999 through 1 August 2020. We found forty publications with fifty-eight eligible cases. A second search for publications dealing with genetic risk factors for CBS led to the review of eight additional ar

SUBMITTER: Arienti F 

PROVIDER: S-EPMC7830591 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature