Unravelling Heterogeneity of Amplified Human Amniotic Fluid Stem Cells Sub-Populations.

ABSTRACT: Human amniotic fluid stem cells (hAFSCs) are broadly multipotent immature progenitor cells with high self-renewal and no tumorigenic properties. These cells, even amplified, present very variable morphology, density, intracellular composition and stemness potential, and this heterogeneity can hinder their characterization and potential use in regenerative medicine. Celector^® (Stem Sel ltd.) is a new technology that exploits the Non-Equilibrium Earth Gravity Assisted Field Flow Fractionation principles to characterize and label-free sort stem cells based on their solely physical characteristics without any manipulation. Viable cells are collected and used for further studies or direct applications. In order to understand the intrapopulation heterogeneity, various fractions of hAF

SUBMITTER: Casciaro F 

PROVIDER: S-EPMC7830644 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature