Regenerative Approaches and Future Trends for the Treatment of Corneal Burn Injuries.

ABSTRACT: Ocular chemical and thermal burns are frequent causes of hospitalization and require immediate interventions and care. Various surgical and pharmacological treatment strategies are employed according to damage severity. Controlling inflammation and neovascularization while promoting normal ocular surface anatomy and function restoration is the principal aim. In the most severe cases, when epithelial healing is severely affected, reconstruction of the ocular surface may be a valid option, which, however, requires expertise, adequate instruments, and qualified donors. Numerous endogenous and exogenous strategies have been considered for corneal repair. Among these, stem cells and their derivatives have offered numerous attractive possibilities in finding an effective way in stimulating corne

SUBMITTER: Saccu G 

PROVIDER: S-EPMC7830803 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature