Group A emergency-release plasma in trauma patients requiring massive transfusion.

ABSTRACT:

Background

Both groups A and AB plasma have been approved for emergency-release transfusion in acutely bleeding trauma patients before blood grouping being performed. The safety profile associated with this practice has not been well characterized, particularly in patients requiring massive transfusion.

Methods

This secondary analysis of the Pragmatic, Randomized, Optimal Platelet and Plasma Ratios trial examined whether exposure to group A emergency-release plasma (ERP) was noninferior to group AB ERP. We also examined patients whose blood groups were compatible with group A ERP versus patients whose blood groups were incompatible with group A ERP. Outcomes included 30-day mortality and complication rates including systemic inflammatory response syndrome, infection, renal i

SUBMITTER: de Roulet A 

PROVIDER: S-EPMC7830815 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature