Osteosarcoma Pathogenesis Leads the Way to New Target Treatments.

ABSTRACT: Osteosarcoma (OS) is a rare condition with very poor prognosis in a metastatic setting. Basic research has enabled a better understanding of OS pathogenesis and the discovery of new potential therapeutic targets. Phase I and II clinical trials are already ongoing, with some promising results for these patients. This article reviews OS pathogenesis and new potential therapeutic targets.

SUBMITTER: Fernandes I 

PROVIDER: S-EPMC7831017 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature