Putting Cells in Motion: Advantages of Endogenous Boosting of BDNF Production.

ABSTRACT: Motor exercise, such as sport or musical activities, helps with a plethora of diseases by modulating brain functions in neocortical and subcortical regions, resulting in behavioural changes related to mood regulation, well-being, memory, and even cognitive preservation in aging and neurodegenerative diseases. Although evidence is accumulating on the systemic neural mechanisms mediating these brain effects, the specific mechanisms by which exercise acts upon the cellular level are still under investigation. This is particularly the case for music training, a much less studied instance of motor exercise than sport. With regards to sport, consistent neurobiological research has focused on the brain-derived neurotrophic factor (BDNF), an essential player in the central nervous system. BDNF sti

SUBMITTER: Brattico E 

PROVIDER: S-EPMC7831493 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature