Biomarkers and short-term prognosis in COVID-19.

ABSTRACT:

Purpose

The aim of our study was to analyse the short-term prognostic value of different biomarkers in patients with COVID-19.

Methods

We included patients admitted to emergency department with COVID-19 and available concentrations of cardiac troponin I (cTnI), D-dimer, C-reactive protein (CRP) and lactate dehydrogenase (LDH). Patients were classified for each biomarker into two groups (low vs. high concentrations) according to their best cut-off point, and 30-day all-cause death was evaluated.

Results

After multivariate adjustment, cTnI ≥21 ng/L, D-dimer ≥1112 ng/mL, CRP ≥10 mg/dL and LDH ≥334 U/L at admission were associated with an increased risk of 30-day all-cause death (hazard ratio (HR) 4.30; 95% CI 1.74-10.58; p = 0.002; HR 3.35; 95% CI 1.58-7.13; p<

SUBMITTER: Peiro OM 

PROVIDER: S-EPMC7832452 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature