Retrospective study identifies infection related risk factors in close contacts during COVID-19 epidemic.

ABSTRACT:

Objectives

This study aimed to compare the risk of infection of children with that of adults and to explore risk factors of infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) by following up close contacts of COVID-19 patients.

Method

The retrospective cohort study was performed among close contacts of index cases diagnosed with COVID-19 in Guangzhou, China. Demographic characteristics, clinical symptoms and exposure information were extracted. Logistic regression analysis was employed to explore the risk factors. The restricted cubic spline was conducted to examine to the dose-response relationship between age and SARS-CoV-2 infection.

Results

The secondary attack rate (SAR) was 4.4% in 1,344 close contacts. The group of household contacts (1

SUBMITTER: Hu P 

PROVIDER: S-EPMC7832759 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature