T cell response to SARS-CoV-2 infection in humans: A systematic review.

ABSTRACT:

Background

Understanding the T cell response to SARS-CoV-2 is critical to vaccine development, epidemiological surveillance and disease control strategies. This systematic review critically evaluates and synthesises the relevant peer-reviewed and pre-print literature published from 01/01/2020-26/06/2020.

Methods

For this systematic review, keyword-structured literature searches were carried out in MEDLINE, Embase and COVID-19 Primer. Papers were independently screened by two researchers, with arbitration of disagreements by a third researcher. Data were independently extracted into a pre-designed Excel template and studies critically appraised using a modified version of the MetaQAT tool, with resolution of disagreements by consensus. Findings were narratively synthesised.

SUBMITTER: Shrotri M 

PROVIDER: S-EPMC7833159 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature