Low vitamin D status is associated with coronavirus disease 2019 outcomes: a systematic review and meta-analysis.

ABSTRACT:

Background

Observational studies suggest that the risk and clinical prognosis of coronavirus disease 2019 (COVID-19) are related to low vitamin D status; however, the data are inconsistent.

Objectives

We conducted a systematic review and meta-analysis to assess the association between low vitamin D status and COVID-19.

Methods

A systematic search was conducted with PubMed, Embase, and the Cochrane Library from database inception to September 25, 2020. The standardized mean difference (SMD) or odds ratio (OR) and corresponding 95% confidence interval (CI) was applied to estimate pooled results. Random - or fixed-effect models based on heterogeneity were used for the meta-analysis. Funnel plots and Egger regression tests were used to assess publication bias.

Results<

SUBMITTER: Liu N 

PROVIDER: S-EPMC7833186 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature