Comparative efficacy of platelet-rich plasma applied in myringoplasty: A systematic review and meta-analysis.

ABSTRACT:

Background

Tympanic membrane (TM) perforation is quite common in the clinical setting. Chronic TM perforations require surgical treatments such as myringoplasty. Currently, platelet-rich plasma (PRP) is a novel, effective substance that is increasingly utilized for TM perforation repair. This study aims to evaluate the effectiveness of PRP in the application of TM perforation repair.

Methods

A systematic search was conducted to screen the Medline, Embase, Cochrane, Scopus and Web of Science databases up to July 2020. Studies were identified in accordance with the selection criteria by two coauthors independently. Data regarding the healing and hearing outcomes were pooled and analyzed via Review Manager version 5.3 and STATA version 12.0 software. Odds ratio (OR) was utilize

SUBMITTER: Huang J 

PROVIDER: S-EPMC7833258 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature