Clinical applications of detecting IgG, IgM or IgA antibody for the diagnosis of COVID-19: A meta-analysis and systematic review.

ABSTRACT:

Background

The coronavirus disease 2019 (COVID-19) pandemic has had a devastating impact worldwide, and timely detection and quarantine of infected patients are critical to prevent spread of disease. Serological antibody testing is an important diagnostic method used increasingly in clinics, although its clinical application is still under investigation.

Methods

A meta-analysis was conducted to compare the diagnostic performance of severe acute respiratory syndrome coronavirus-2 antibody tests in patients with COVID-19. The test results analysed included: (1) IgM-positive but IgG-negative (IgM⁺IgG^-); (2) IgG-positive but IgM-negative (IgG⁺IgM^-); (3) both IgM-positive and IgG-positive (IgM⁺IgG⁺); (4) IgM-positi

SUBMITTER: Chen M 

PROVIDER: S-EPMC7833601 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature