Results from the IRoc-GN international registry of patients with COVID-19 and glomerular disease suggest close monitoring.

ABSTRACT: The effects of SARS-CoV-2 infection on individuals with immune-mediated glomerulonephritis, who are often undergoing immunosuppressive treatments, are unknown. Therefore, we created the International Registry of COVID infection in glomerulonephritis (IRoc-GN) and identified 40 patients with glomerulonephritis and COVID-19 followed in centers in North America and Europe. Detailed information on glomerulonephritis diagnosis, kidney parameters, and baseline immunosuppression prior to infection were recorded, as well as clinical presentation, laboratory values, treatment, complications, and outcomes of COVID-19. This cohort was compared to 80 COVID-positive control cases from the general population without glomerulonephritis matched for the time of infection. The majority (70%) of the patients

SUBMITTER: Waldman M 

PROVIDER: S-EPMC7833801 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature