Cardiac Troponin for Assessment of Myocardial Injury in COVID-19: JACC Review Topic of the Week.

ABSTRACT: Increases in cardiac troponin indicative of myocardial injury are common in patients with coronavirus disease-2019 (COVID-19) and are associated with adverse outcomes such as arrhythmias and death. These increases are more likely to occur in those with chronic cardiovascular conditions and in those with severe COVID-19 presentations. The increased inflammatory, prothrombotic, and procoagulant responses following severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection increase the risk for acute nonischemic myocardial injury and acute myocardial infarction, particularly type 2 myocardial infarction, because of respiratory failure with hypoxia and hemodynamic instability in critically ill patients. Myocarditis, stress cardiomyopathy, acute heart failure, and direct injury from

SUBMITTER: Sandoval Y 

PROVIDER: S-EPMC7833921 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature