Disrupting enzyme fluidity.

ABSTRACT: A combination of X-ray crystallography, NMR, and mass spectrometry has revealed how diverse small-molecule inhibitors bind Bruton's tyrosine kinase and alter the conformation of this enzyme.

SUBMITTER: Anand GS 

PROVIDER: S-EPMC7834015 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature