Predictors for development of critical illness amongst older adults with COVID-19: Beyond age to age-associated factors.

ABSTRACT:

Introduction

Older adults with COVID-19 have disproportionately higher rates of severe disease and mortality. It is unclear whether this is attributable to age or attendant age-associated risk factors. This retrospective cohort study aims to characterize hospitalized older adults and examine if comorbidities, frailty and acuity of clinical presentation exert an age-independent effect on COVID-19 severity.

Methods

We studied 275 patients admitted to the National Centre of Infectious Disease, Singapore. We measured: 1)Charlson Comorbidity Index(CCI) as burden of comorbidities; 2)Clinical Frailty Scale(CFS) and Frailty Index(FI); and 3)initial acuity. We studied characteristics and outcomes of critical illness, stratified by age groups (50-59,60-69 and ≥70). We conducted hierar

SUBMITTER: Lim JP 

PROVIDER: S-EPMC7834606 | biostudies-literature | 2021 May-Jun

REPOSITORIES: biostudies-literature