Reporting and design of randomized controlled trials for COVID-19: A systematic review.

ABSTRACT:

Background

The novel coronavirus 2019 (COVID-19) pandemic has mobilized global research at an unprecedented scale. While challenges associated with the COVID-19 trial landscape have been discussed previously, no comprehensive reviews have been conducted to assess the reporting, design, and data sharing practices of randomized controlled trials (RCTs).

Purpose

The purpose of this review was to gain insight into the current landscape of reporting, methodological design, and data sharing practices for COVID-19 RCTs.

Data sources

We conducted three searches to identify registered clinical trials, peer-reviewed publications, and pre-print publications.

Study selection

After screening eight major trial registries and 7844 records, we identified 178 registered trials

SUBMITTER: Dillman A 

PROVIDER: S-EPMC7834682 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature