The burden of liver cirrhosis and underlying etiologies: results from the global burden of disease study 2017.

ABSTRACT:

Background

To evaluate the pattern and prevalence trends of liver cirrhosis caused by specific etiologies.

Results

Globally, the number of prevalent cases increased 74.53% from 1990 to 2017. The ASR increased 0.75 per year. The most pronounced increases were found in middle-high and high socio-demographic index (SDI) regions, especially in the Caribbean and Latin America. Among the etiologies, non-alcoholic steatohepatitis (NASH) related liver cirrhosis accounted for 59.46% of the cases. The ASR increased 1.74 per year, and the increase was observed in all 5 SDI regions. In addition, the ASR of liver cirrhosis caused by alcohol also increased in both sexes and all SDI regions. In contrast, the ASR of liver cirrhosis caused by hepatitis B virus (HBV) and hepatitis C virus (HC

SUBMITTER: Zhai M 

PROVIDER: S-EPMC7835066 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature