Faster age-related decline in cardiorespiratory fitness in rheumatoid arthritis patients: an observational study in the Trondelag Health Study.

ABSTRACT: Primary aim: Compare change in estimated cardiorespiratory fitness (eCRF change) in rheumatoid arthritis (RA) patients with population-based age- and sex-matched controls during ~ 11-year follow-up and identify variables associated with eCRF change. Secondary aim: Compare eCRF level in RA patients and controls. eCRF change from the second (HUNT2 1995-1997) to the third (HUNT3 2006-2008) surveys of the Norwegian Trøndelag Health Study was compared between RA patients (n = 188) and controls (n = 26,202) attending both surveys. Predictors of eCRF change were identified by Lasso regression followed by multiple linear regression. Mean eCRF level in RA patients (n = 436) and controls (n = 67,910) was compared using age-adjusted linear regression stratified on sex, as well as two-sample t tests i

SUBMITTER: Liff MH 

PROVIDER: S-EPMC7835174 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature