Early use of corticosteroids in non-critical patients with COVID-19 pneumonia (PREDCOVID): a structured summary of a study protocol for a randomised controlled trial.

ABSTRACT:

Objectives

To evaluate the efficacy of early treatment with prednisone to decrease the progression of COVID-19 pneumonia.

Trial design

This is a pragmatic, non-blinded, randomized, two arms, parallel trial.

Participants

Patients between 18 and 90 years, with COVID-19 pneumonia, confirmed by RT PCR. The setting for the trial is the Hospital Santiago Oriente which is a secondary level hospital with an emergency room, intensive care, and all basic specialties of medicine.

Inclusion criteria

18 years or more COVID-19 confirmed by RT-PCR Oxygen requirements up to 35% by venturi mask or 5 liters per minute by nasal cannula (approximately FiO2 40%) Consent form signed Exclusion Criteria: Previous steroid use for more than 48 hours. Pregnancy Chronic respiratory failur

SUBMITTER: Salinas M 

PROVIDER: S-EPMC7835442 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature