Left atrial function and maximal exercise capacity in heart failure with preserved and mid-range ejection fraction.

ABSTRACT:

Aims

Exercise intolerance is the leading manifestation of heart failure with preserved or mid-range ejection fraction (HFpEF or HFmrEF), and left atrial (LA) function might contribute to modulating left ventricular filling and pulmonary venous pressures. We aim to assess the association between LA function and maximal exercise capacity in patients with HFpEF or HFmrEF.

Methods and results

Sixty-five patients, prospectively enrolled in the German HFpEF Registry, were analysed. Inclusion criteria were New York Heart Association functional class ≥ II, left ventricular ejection fraction > 40%, structural heart disease or diastolic dysfunction, and elevated levels of N terminal pro brain natriuretic peptide (NT-proBNP). LA function was evaluated through speckle-tracking echocardi

SUBMITTER: Maffeis C 

PROVIDER: S-EPMC7835603 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature