Impact of sex differences in co-morbidities and medication adherence on outcome in 25 776 heart failure patients.

ABSTRACT:

Aims

Health insurance claims (HIC) databases in the Netherlands capture unselected patient populations, which makes them suitable for epidemiological research on sex differences. Based on a HIC database, we aimed to reveal sex differences in heart failure (HF) outcomes, with particular focus on co-morbidities and medication.

Methods and results

The Achmea HIC database included 14 517 men and 11 259 (45%) women with a diagnosis treatment code for chronic HF by January 2015. We related their sex, co-morbidities, and medication adherence (medication possession rate >0.8) with the primary endpoint (PE) of all-cause mortality or HF admission during a median follow-up of 3.3 years, using Cox regression. Median age of men and women was 72 and 76 years, respectively. Prevalence of c

SUBMITTER: Gurgoze MT 

PROVIDER: S-EPMC7835621 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature