Weighted Single-Step GWAS Identified Candidate Genes Associated with Growth Traits in a Duroc Pig Population.

ABSTRACT: Growth traits are important economic traits of pigs that are controlled by several major genes and multiple minor genes. To better understand the genetic architecture of growth traits, we performed a weighted single-step genome-wide association study (wssGWAS) to identify genomic regions and candidate genes that are associated with days to 100 kg (AGE), average daily gain (ADG), backfat thickness (BF) and lean meat percentage (LMP) in a Duroc pig population. In this study, 3945 individuals with phenotypic and genealogical information, of which 2084 pigs were genotyped with a 50 K single-nucleotide polymorphism (SNP) array, were used for association analyses. We found that the most significant regions explained 2.56-3.07% of genetic variance for four traits, and the detected significant reg

SUBMITTER: Ruan D 

PROVIDER: S-EPMC7835741 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature