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Potential Herb-Drug Interactions in the Management of Age-Related Cognitive Dysfunction.


ABSTRACT: Late-life mild cognitive impairment and dementia represent a significant burden on healthcare systems and a unique challenge to medicine due to the currently limited treatment options. Plant phytochemicals have been considered in alternative, or complementary, prevention and treatment strategies. Herbals are consumed as such, or as food supplements, whose consumption has recently increased. However, these products are not exempt from adverse effects and pharmacological interactions, presenting a special risk in aged, polymedicated individuals. Understanding pharmacokinetic and pharmacodynamic interactions is warranted to avoid undesirable adverse drug reactions, which may result in unwanted side-effects or therapeutic failure. The present study reviews the potential interactions between se

SUBMITTER: Auxtero MD 

PROVIDER: S-EPMC7835864 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature