Associations Between Caffeine Consumption, Cognitive Decline, and Dementia: A Systematic Review.

ABSTRACT:

Background

Epidemiologic studies have provided inconclusive evidence for a protective effect of caffeine consumption on risk of dementia and cognitive decline.

Objective

To summarize literature on the association between caffeine and 1) the risk of dementia and/or cognitive decline, and 2) cognitive performance in individuals with mild cognitive impairment (MCI) or dementia, and 3) to examine the effect of study characteristics by categorizing studies based on caffeine source, quantity and other possible confounders.

Methods

We performed a systematic review of caffeine effects by assessing overall study outcomes; positive, negative or no effect. Our literature search identified 61 eligible studies performed between 1990 and 2020.

Results

For studies analyzing t

SUBMITTER: Chen JQA 

PROVIDER: S-EPMC7836063 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature