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Computed optical spectra of SARS-CoV-2 proteins.

ABSTRACT: Treatment for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes Covid-19, may well be predicated on knowledge of the structures of protein of this virus. However, often these cannot be determined easily or quickly. Herein, we provide calculated circular dichroism (CD) spectra in the far- and near-UV, and infra-red (IR) spectra in the amide I region for experimental structures and computational models of SARS-CoV-2 proteins. The near-UV CD spectra offer greatest sensitivity in assessing the accuracy of models.

SUBMITTER: Li Z

PROVIDER: S-EPMC7836526 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Computed optical spectra of SARS-CoV-2 proteins.

Li Zhuo Z Hirst Jonathan D JD

Chemical physics letters 20200829

Treatment for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes Covid-19, may well be predicated on knowledge of the structures of protein of this virus. However, often these cannot be determined easily or quickly. Herein, we provide calculated circular dichroism (CD) spectra in the far- and near-UV, and infra-red (IR) spectra in the amide I region for experimental structures and computational models of SARS-CoV-2 proteins. The near-UV CD spectra offer greatest ...[more]

PMID: 33518776

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