Quantitative proteomics-based analyses performed on pre-eclampsia samples in the 2004-2020 period: a systematic review.

ABSTRACT:

Background

Quantitative proteomics is an invaluable tool in biomedicine for the massive comparative analysis of protein component of complex biological samples. In the last two decades, this technique has been used to describe proteins potentially involved in the pathophysiological mechanisms of preeclampsia as well as to identify protein biomarkers that could be used with diagnostic/prognostic purposes in pre-eclampsia.

Results

We have done a systematic review of all proteomics-based papers describing differentially expressed proteins in this disease. Searching Pubmed with the terms pre-eclampsia and proteomics, restricted to the Title/Abstract and to MeSH fields, and following manual curation of the original list, retrieved 69 original articles corresponding to the 2004-20

SUBMITTER: Navajas R 

PROVIDER: S-EPMC7836571 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature