A Comprehensive Systematic Review of CSF analysis that defines Neurological Manifestations of COVID-19.

ABSTRACT:

Background

Limited literature exists on Cerebrospinal fluid (CSF) findings in COVID-19 patients with neurological symptoms. In this review, we conducted a descriptive analysis of CSF findings in patients with COVID-19 to understand prognosis and explore therapeutic options.

Methods

We searched PubMed, Google Scholar, and Scopus databases using the keywords "SARS-CoV-2 in cerebrospinal fluid" and "SARS-CoV-2 and CNS Complications"" for reports of CSF findings in COVID-19 related neurological manifestations. Descriptive analyses were conducted to observe the CSF protein and cell counts based on age, gender, severity, fatality of COVID-19, and whether central (CNS) or peripheral nervous system (PNS) was associated.

Results

A total of 113 patients were identified from 67

SUBMITTER: Tandon M 

PROVIDER: S-EPMC7837002 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature