Ontology highlight
ABSTRACT:
SUBMITTER: Valdes-Aleman J
PROVIDER: S-EPMC7837116 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Valdes-Aleman Javier J Fetter Richard D RD Sales Emily C EC Heckman Emily L EL Venkatasubramanian Lalanti L Doe Chris Q CQ Landgraf Matthias M Cardona Albert A Zlatic Marta M
Neuron 20201028 1
The mechanisms by which synaptic partners recognize each other and establish appropriate numbers of connections during embryonic development to form functional neural circuits are poorly understood. We combined electron microscopy reconstruction, functional imaging of neural activity, and behavioral experiments to elucidate the roles of (1) partner identity, (2) location, and (3) activity in circuit assembly in the embryonic nerve cord of Drosophila. We found that postsynaptic partners are able ...[more]