Current status and future directions in unresectable stage III non-small cell lung cancer.

ABSTRACT:

Background

Patients with unresectable stage III non-small-cell lung cancer constitute a heterogeneous group in which the available treatments may range from radical therapies with radio-chemotherapy to supportive treatments depending on the extent of the disease and comorbidities present. For years the standard treatment based on the combination of chemotherapy and radiotherapy (RT) has remained unchanged and survival outcomes have been poor.

Aim

Recent advances in molecular biology and RT technology have resulted in improved survival. This article reviews the treatments that constitute current standard treatment in unresectable advanced lung cancer and the situations and indications for the management of patients who are not candidates for radical therapy.

Relevance for

SUBMITTER: Arellano EA 

PROVIDER: S-EPMC7837736 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature