Identifying Signatures of Selection Related to Comb Development.

ABSTRACT: The aim of this study was to identify genes involved in comb development to provide insights into the molecular mechanism of chickens' comb formation. Fixation index (F_ST) and average number of base differences (π) of males with large and small combs were calculated based on whole-genome resequencing data. Chromosome regions with larger F_ST values and smaller π were considered candidate selection regions. Through further annotation of gene functions and pathways, we sought to screen possible selected genes associated with comb development. By screening whole genome resequencing data, F_ST and π were calculated using a 40 Kb sliding window strategy and eight regions were identified. Quantitative trait loci (QTL; FOX1 gene) related

SUBMITTER: Tu Y 

PROVIDER: S-EPMC7837803 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature