Changes in fasting bile acid profiles after Roux-en-Y gastric bypass and sleeve gastrectomy.

ABSTRACT:

Background

Bile acid is an essential factor that plays a role in metabolic regulation, but how bile acid is regulated after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) remains unclear. This meta-analysis aimed to investigate changes in the levels of fasting bile acids following RYGB and SG.

Methods

A systematic literature search of the PubMed, EMBASE, Cochrane Library and Web of Science databases through July 2020 was performed in accordance with the Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. The concentrations of bile acids were evaluated.

Results

Thirteen studies with 289 patients were included. Our results showed that patients wh

SUBMITTER: Zhang C 

PROVIDER: S-EPMC7837931 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature