Association Between Early Invasive Mechanical Ventilation and Day-60 Mortality in Acute Hypoxemic Respiratory Failure Related to Coronavirus Disease-2019 Pneumonia.

ABSTRACT:

Objectives

About 5% of patients with coronavirus disease-2019 are admitted to the ICU for acute hypoxemic respiratory failure. Opinions differ on whether invasive mechanical ventilation should be used as first-line therapy over noninvasive oxygen support. The aim of the study was to assess the effect of early invasive mechanical ventilation in coronavirus disease-2019 with acute hypoxemic respiratory failure on day-60 mortality.

Design

Multicenter prospective French observational study.

Setting

Eleven ICUs of the French OutcomeRea network.

Patients

Coronavirus disease-2019 patients with acute hypoxemic respiratory failure (Pao₂/Fio₂ ≤ 300 mm Hg), without shock or neurologic failure on ICU admission, and not referred from another ICU or int

SUBMITTER: Dupuis C 

PROVIDER: S-EPMC7838010 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature