Detecting the Multiomics Signatures of Factor-Specific Inflammatory Effects on Airway Smooth Muscles.

ABSTRACT: Smooth muscles are a specific muscle subtype that is widely identified in the tissues of internal passageways. This muscle subtype has the capacity for controlled or regulated contraction and relaxation. Airway smooth muscles are a unique type of smooth muscles that constitute the effective, adjustable, and reactive wall that covers most areas of the entire airway from the trachea to lung tissues. Infection with SARS-CoV-2, which caused the world-wide COVID-19 pandemic, involves airway smooth muscles and their surrounding inflammatory environment. Therefore, airway smooth muscles and related inflammatory factors may play an irreplaceable role in the initiation and progression of several severe diseases. Many previous studies have attempted to reveal the potential relationships between inte

SUBMITTER: Zhang YH 

PROVIDER: S-EPMC7838645 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature