Outcomes of Kidney Transplantation in Fabry Disease: A Meta-Analysis.

ABSTRACT:

Background

Fabry disease (FD) is a rare X-linked lysosomal storage disorder with progressive systemic deposition of globotriaosylceramide, leading to life-threatening cardiac, central nervous system, and kidney disease. Current therapy involves symptomatic medical management, enzyme replacement therapy (ERT), dialysis, kidney transplantation, and, more recently, gene therapy. The aim of this systematic review was to assess outcomes of kidney transplantation among patients with FD.

Methods

A comprehensive literature review was conducted utilizing MEDLINE, EMBASE, and Cochrane Database, from inception through to 28 February 2020, to identify studies that evaluate outcomes of kidney transplantation including patient and allograft survival among kidney transplant patients with F

SUBMITTER: Suarez MLG 

PROVIDER: S-EPMC7838795 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature