Ontology highlight
ABSTRACT:
SUBMITTER: Agrawal L
PROVIDER: S-EPMC7839017 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Agrawal Lokesh L Poullikkas Thanasis T Eisenhower Scott S Monsanto Carlo C Bakku Ranjith Kumar RK Chen Min-Hua MH Kalra Rajkumar Singh RS
Antibodies (Basel, Switzerland) 20210111 1
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel coronavirus for which no known effective antiviral drugs are available. In the present study, to accelerate the discovery of potential drug candidates, bioinformatics-based in silico drug discovery approaches are utilized. We performed multiple sequence alignments of the Spike (S) protein with 75 sequences of different viruses from the Orthocoronavirinae subfamily. This provided us with insights into the evolutionarily conse ...[more]