Risk of dementia in adults with cerebral palsy: a matched cohort study using general practice data.

ABSTRACT:

Objectives

Determine the risk of incident dementia in adults with cerebral palsy (CP) compared with age, sex and general practice (GP) matched controls.

Design

Retrospective cohort study.

Setting

UK GPs linked into the Clinical Practice Research Datalink (CPRD).

Participants

CPRD data were used to identify adults aged 18 or older with a diagnosis of CP. Each adult with CP was matched to three controls who were matched for age, sex and GP. In total, 1703 adults with CP and 5109 matched controls were included in the analysis. The mean baseline age of participants was 33.30 years (SD: 15.48 years) and 46.8% of the sample were female.

Primary outcome

New diagnosis of dementia during the follow-up period (earliest date of 1987 to latest date of 2015).

Resu

SUBMITTER: Smith KJ 

PROVIDER: S-EPMC7839844 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature