Noninvasive ventilation in critically ill very old patients with pneumonia: A multicenter retrospective cohort study.

ABSTRACT:

Background

Very old patients (≥ 80 years-old, VOP) are increasingly admitted to intensive care units (ICUs). Community-acquired pneumonia (CAP) is a common reason for admission and the best strategy of support for respiratory failure in this scenario is not fully known. We evaluated whether noninvasive ventilation (NIV) would be beneficial compared to invasive mechanical ventilation (IMV) regarding hospital mortality.

Methods

Multicenter cohort study of VOPs admitted with CAP in need of IMV or NIV to 11 Brazilian ICUs from 2009 through 2012. We used logistic regression models to evaluate the association between the initial ventilatory strategy (NIV vs. IMV) and hospital mortality adjusting for confounding factors. We evaluated effect modification with interaction terms in pr

SUBMITTER: Besen BAMP 

PROVIDER: S-EPMC7840033 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature