Gamma Oscillations Facilitate Effective Learning in Excitatory-Inhibitory Balanced Neural Circuits.

ABSTRACT: Gamma oscillation in neural circuits is believed to associate with effective learning in the brain, while the underlying mechanism is unclear. This paper aims to study how spike-timing-dependent plasticity (STDP), a typical mechanism of learning, with its interaction with gamma oscillation in neural circuits, shapes the network dynamics properties and the network structure formation. We study an excitatory-inhibitory (E-I) integrate-and-fire neuronal network with triplet STDP, heterosynaptic plasticity, and a transmitter-induced plasticity. Our results show that the performance of plasticity is diverse in different synchronization levels. We find that gamma oscillation is beneficial to synaptic potentiation among stimulated neurons by forming a special network structure where the sum of ex

SUBMITTER: Li KT 

PROVIDER: S-EPMC7840255 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature