Effect of adjuvant bisphosphonates on treatment of periodontitis: Systematic review with meta-analyses.

ABSTRACT:

Background

Previous systematic reviews showed additional benefit of adjuvant bisphosphonates (BP) in the treatment of periodontitis. In contrast, it is unclear the effect of BP in patients with diabetes and smokers, its pooled effect when administered locally or systemically is also unknown.

Objectives

This study aimed to systematically review the literature about the use of BP as adjuvant to nonsurgical scaling and root planning (SRP).

Methodology

This study followed the PRISMA guideline. This study included randomized clinical trials that administered locally or systemically BPs as adjuvant for periodontal treatment. Five databases were used. Meta-analyses were performed, using the pooled mean differences (MD) for clinical attachment level (CAL) and probing pocket d

SUBMITTER: Muniz FWMG 

PROVIDER: S-EPMC7841362 | biostudies-literature | 2021 Apr-Jun

REPOSITORIES: biostudies-literature