Fronto-parietal involvement in chronic stroke motor performance when corticospinal tract integrity is compromised.

ABSTRACT:

Background

Preserved integrity of the corticospinal tract (CST) is a marker of good upper-limb behavior and recovery following stroke. However, there is less understanding of neural mechanisms that might help facilitate upper-limb motor recovery in stroke survivors with extensive CST damage.

Objective

The purpose of this study was to investigate resting state functional connectivity in chronic stroke survivors with different levels of CST damage and to explore neural correlates of greater upper-limb motor performance in stroke survivors with compromised ipsilesional CST integrity.

Methods

Thirty chronic stroke survivors (24 males, aged 64.7 ± 10.8 years) participated in this study. Three experimental sessions were conducted to: 1) obtain anatomical (T1, T2) structural

SUBMITTER: Hordacre B 

PROVIDER: S-EPMC7841401 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature